ln order to improve the information literacy and practical ability of college students , based onMathstudio,its application in five modern physics experimental data processing is introduced, and theprocessing results are also compared with those of other data processing software.The results show that:Ccompared with the traditional methods of manual calculation and computer-side software operation, theMathstudio-based method of modern physics experimental data processing provides technical support andconvenience for college students in symbolic operations, data input or output and curve fitting; 2) theMathstudio-based method of modern physics experimental data processing demonstrated enriches thesmartphone in physics experimental, which is important to accelerate the research and practice of teachinginformatization reform and to enhance the deep integration of students information literacy and practica ability.